CHEMICAL INVESTIGATIONS OF THE CENTRAL NERVOUS SYSTEM UNDER NORMAL AND PATHOLOGIC CONDITIONS

ADENOSINE IN THE CENTRAL NERVOUS SYSTEM

Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mecha...

Chemical mediators in the central nervous system.

Chemical transmission in the central nervous system.

Investigations on the regional determination of the central nervous system.

INTRODUCTION Among the experiments to elucidate the origin of the germ cells in the Urodeles (Nieuwkoop, 1946), one experimental series was investigated, in which the dorsal blastoporal lip of one embryo was transplanted to the presumptive ventral lip of another (cf. Spemann, 1918, 1931a). In order to investigate the development of the germ cells, experimental animals must be reared to an age a...

Primary central nervous system lymphoma: CT and pathologic correlation.

CT findings of 15 patients with histologically proven primary central nervous system (CNS) lymphoma were reviewed with pathologic correlation in order to evaluate variable CT patterns. There were a total of 32 lesions. Of the 15 patients studied, seven had acquired immunodeficiency syndrome (AIDS), all diagnosed within the past 3 years. The CT observations of eight non-AIDS patients were consis...